Robert A Bonomo Selected Research

beta-Lactamases (beta-Lactamase)

1/2021	A Multicentered Study of the Clinical and Molecular Epidemiology of TEM- and SHV-type Extended-Spectrum Beta-Lactamase Producing Enterobacterales Infections in Children.
7/2010	Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase.
10/2009	Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein.
10/2007	Overcoming resistance to beta-lactamase inhibitors: comparing sulbactam to novel inhibitors against clavulanate resistant SHV enzymes with substitutions at Ambler position 244.
5/2007	Crystal structure of KPC-2: insights into carbapenemase activity in class A beta-lactamases.
12/2006	Extended-spectrum beta-lactamases in multidrug-resistant Escherichia coli: changing the therapy for hospital-acquired and community-acquired infections.
7/2004	Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases.
1/2004	International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum beta-lactamase production in nosocomial Infections.
12/2002	Unexpected advanced generation cephalosporinase activity of the M69F variant of SHV beta-lactamase.

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Robert A Bonomo Research Topics

Disease

129	Infections 04/2022 - 12/2002
23	Sepsis (Septicemia) 01/2022 - 12/2006
10	Respiratory Sounds (Crackle) 01/2022 - 04/2015
10	Cross Infection (Nosocomial Infection) 01/2022 - 01/2004
10	Bacteremia 09/2020 - 01/2004
9	Urinary Tract Infections (Urinary Tract Infection) 04/2022 - 12/2008
9	Communicable Diseases (Infectious Diseases) 04/2022 - 12/2012
8	Bacterial Infections (Bacterial Infection) 01/2022 - 09/2006
7	Pneumonia (Pneumonitis) 01/2022 - 07/2004
5	Wounds and Injuries (Trauma) 07/2017 - 10/2007
4	Meningitis 01/2021 - 05/2013
4	Septic Shock (Toxic Shock Syndrome) 01/2017 - 01/2016
3	COVID-19 01/2022 - 01/2021
3	Persistent Infection 01/2022 - 10/2013
3	Osteomyelitis 05/2020 - 11/2019
3	Neoplasms (Cancer) 07/2018 - 11/2014
3	Soft Tissue Infections 07/2018 - 12/2008
3	Cystic Fibrosis (Mucoviscidosis) 01/2017 - 04/2011
3	Gram-Negative Bacterial Infections 11/2014 - 10/2009
2	Starvation 01/2022 - 01/2018
2	Acute Kidney Injury (Acute Renal Failure) 11/2020 - 01/2019
2	Central Nervous System Infections (Central Nervous System Infection) 09/2020 - 10/2013
2	Diabetes Mellitus 01/2020 - 09/2003
2	Diabetic Foot 01/2020 - 11/2019
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2019 - 07/2002
2	Pseudomonas Infections 12/2018 - 10/2005
2	Intraabdominal Infections 01/2016 - 12/2008
2	Fibrosis (Cirrhosis) 01/2016 - 02/2010
2	Melioidosis 12/2015 - 01/2011
2	Critical Illness (Critically Ill) 04/2015 - 01/2014
2	Tuberculosis (Tuberculoses) 12/2013 - 09/2012
2	Brain Abscess (Abscess, Brain) 12/2012 - 07/2012
2	Neutropenia 07/2012 - 01/2011
2	Wound Infection (Wound Infections) 01/2012 - 11/2010

Drug/Important Bio-Agent (IBA)

64	Anti-Bacterial Agents (Antibiotics)IBA 04/2022 - 07/2002
57	Carbapenems (Carbapenem Antibiotics)IBA 04/2022 - 07/2004
24	Pharmaceutical PreparationsIBA 08/2021 - 10/2005
20	LactamsIBA 04/2022 - 01/2012
14	ceftazidime drug combination avibactamIBA 01/2021 - 01/2016
13	Colistin (Coly-Mycin)FDA Link 07/2021 - 10/2005
9	beta-Lactamases (beta-Lactamase)IBA 01/2021 - 12/2002
8	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2021 - 11/2004
8	carbapenemaseIBA 01/2020 - 03/2011
7	EnzymesIBA 01/2022 - 12/2002
7	Ceftazidime (Fortum)FDA LinkGeneric 12/2018 - 04/2003
6	AminoglycosidesIBA 11/2020 - 12/2010
6	beta-LactamsIBA 01/2019 - 05/2004
6	Cefepime (Maxipime)FDA LinkGeneric 01/2019 - 10/2005
6	Tigecycline (Tygacil)FDA Link 03/2016 - 12/2010
5	Polymyxins (Polymyxin)IBA 11/2020 - 12/2010
5	beta-Lactamase InhibitorsIBA 01/2019 - 05/2004
5	Fosfomycin FDA Link 01/2019 - 02/2013
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2017
4	CytokinesIBA 01/2021 - 09/2015
4	Aztreonam FDA LinkGeneric 01/2020 - 01/2004
4	Ampicillin (Omnipen)FDA LinkGeneric 12/2017 - 10/2007
4	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 12/2013 - 09/2006
3	Meropenem (Merrem)FDA LinkGeneric 10/2021 - 04/2019
3	Anti-Infective Agents (Microbicides)IBA 01/2021 - 06/2013
3	Virulence Factors (Pathogenicity Factors)IBA 01/2021 - 06/2014
3	Rifampin (Rifampicin)FDA LinkGeneric 01/2020 - 04/2019
3	Imipenem FDA Link 10/2019 - 01/2016
3	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 01/2019 - 04/2003
3	IronIBA 01/2019 - 03/2016
3	Peptides (Polypeptides)IBA 09/2015 - 11/2010
3	VaccinesIBA 04/2014 - 01/2012
2	CefiderocolIBA 01/2022 - 05/2020
2	SiderophoresIBA 01/2022 - 05/2020
2	ZincIBA 01/2022 - 12/2017
2	Monoclonal AntibodiesIBA 12/2021 - 01/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 01/2017
2	Nucleic AcidsIBA 01/2021 - 01/2014
2	InterleukinsIBA 01/2021 - 01/2017
2	tazobactam drug combination ceftolozaneIBA 11/2020 - 01/2017
2	LN 1-255IBA 10/2019 - 11/2017
2	Third Generation CephalosporinsIBA 01/2019 - 01/2019
2	FluoroquinolonesIBA 01/2019 - 06/2014
2	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 05/2018 - 01/2004
2	N-desmethylstobadineIBA 01/2018 - 04/2016
2	relebactamIBA 01/2018 - 01/2016
2	avibactamIBA 01/2017 - 01/2011
2	Amino Acids FDA Link 01/2012 - 10/2007
2	Amoxicillin (Wymox)FDA LinkGeneric 01/2010 - 09/2006
2	Penicillins (Penicillin)FDA Link 01/2010 - 09/2008
2	beta Lactam AntibioticsIBA 10/2009 - 01/2004
2	Vancomycin FDA LinkGeneric 02/2008 - 04/2003
2	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 02/2008 - 04/2003
2	Cefotaxime (Kendrick)FDA LinkGeneric 01/2004 - 04/2003
1	durlobactamIBA 01/2022

Therapy/Procedure

47	Therapeutics 01/2022 - 07/2002
4	Length of Stay 01/2021 - 01/2014
4	Long-Term Care 01/2019 - 12/2012
3	Debridement 05/2020 - 09/2003
3	Drug Therapy (Chemotherapy) 01/2016 - 05/2009
2	Central Venous Catheters 02/2022 - 10/2017
2	Precision Medicine 01/2022 - 01/2016
2	Transplantation 01/2017 - 12/2010
1	Liver Transplantation 04/2022
1	Critical Care (Surgical Intensive Care) 04/2022
1	Internal Fixators 02/2022